Aaron Sassoon, M.D., Ph.D.

Aaron Sassoon, M.D., Ph.D.

Surgical & Clinical Pathologist

Special Interests

  • Gastrointestinal Pathology
  • Genitourinary Pathology
  • Pediatric Pathology


  • Medical Director
    Children’s Hospital of Orange County (CHOC)
  • President
    Orange County Pathology Medical Group


  • Doctor of Medicine
    University of Southern California (USC)
  • Doctor of Philosophy in Cellular Biology
    University of Southern California (USC)


  • Anatomic Pathology & Clinical Pathology
    University of California, UCLA


  • Hematopathology
    Cedars-Sinai Medical Center

Board Certified in

  • Anatomic Pathology
  • Clinical Pathology
  • Hematopathology


  • Said JW, Nash G, Banks-Schlegel S, Sassoon AF, Murakami S, Shintaku IP. Keratin in human lung tumors. Patterns of localization of different-molecular-weight keratin proteins. Am J Pathol. 1983 Oct;113(1):27-32. PMID: 6194690. PMCID: PMC1916295.
  • Said JW, Nash G, Sassoon AF, Shintaku IP, Banks-Schlegel S. Involucrin in lung tumors. A specific marker for squamous differentiation. Lab Invest. 1983 Nov;49(5):563-8. PMID: 6195449.
  • Said JW, Shintaku IP, Chien K, Sassoon AF. Peripheral T cell lymphoma (immunoblastic sarcoma of T cell type): An immuno-ultrastructural study. Hum Pathol. 1984 Apr;15(4):324-9. PMID: 6609115.
  • Said JW, Nash G, Banks-Schlegel S, Sassoon AF, Shintaku IP. Localized fibrous mesothelioma: An immunohistochemical and electron microscopic study. Hum Pathol. 1984 May;15(5):440-3. PMID: 6202620.
  • Walts AE, Said JW, Shintaku IP, Sassoon AF, Banks-Schlegel S. Keratins of different molecular weight in exfoliated mesothelial and adenocarcinoma cells -- an aid to cell identification. Am J Clin Pathol. 1984 Apr;81(4):442-6. PMID: 6199968.
  • Said JW, Sassoon AF, Shintaku IP, Banks-Schlegel S. Involucrin in squamous and basal cell carcinomas of the skin: An immunohistochemical study. J Invest Dermatol. 1984 May;82(5):449-52. PMID: 6210326.
  • Said JW, Shintaku IP, Teitelbaum A, Chien K, Sassoon AF. Distribution of T-cell phenotypic subsets and surface immunoglobulin-bearing lymphocytes in lymph nodes from male homosexuals with persistent generalized adenopathy: An immunohistochemical and ultrastructural study. Hum Pathol. 1984 Aug;15(8):785- 90. PMID: 6235166.
  • Said JW, Vimadalal S, Nash G, Shintaku IP, Heusser RC, Sassoon AF, Lloyd RV. Immunoreactive neuron-specific enolase, bombesin, and chromogranin as markers for neuroendocrine lung tumors. Hum Pathol. 1985 Mar;16(3):236-40. PMID: 3972403.
  • Sassoon AF, Said JW, Nash G, Shintaku IP, Banks-Schlegel S. Involucrin in intraepithelial and invasive squamous cell carcinomas of the cervix: An immunohistochemical study. Hum Pathol. 1985 May;16(5):467-70. PMID: 3886522.
  • Said JW, Sassoon AF, Shintaku IP, Chien K, Pinkus GS. Immuno-ultrastructural localization of B-cell-specific monoclonal antibodies B1 and B2. J Histochem Cytochem. 1986 May;34(5):607-11. PMID: 3517145.
  • Said JW, Sassoon AF, Chien K, Shintaku IP, Pinkus GS. Immunoultrastructural and morphometric analysis of B lymphocytes in human germinal centers. Evidence for alternate pathways of follicular transformation. Am J Pathol. 1986 May;123(2):390-7. PMID: 2422945. PMCID: PMC1888308.
  • Said JW, Sassoon AF, Shintaku IP, Corcoran P, Nichols SW. Polymerase chain reaction for bcl-2 in diagnostic lymph node biopsies. Mod Pathol. 1990 Nov;3(6):659-63. PMID: 2263590.
  • Said JW, Sassoon AF, Shintaku IP, Kurtin PJ, Pinkus GS. Absence of bcl-2 major breakpoint region and JH gene rearrangement in lymphocyte predominance Hodgkin’s disease. Results of Southern blot analysis and polymerase chain reaction. Am J Pathol. 1991 Feb;138(2):261-4. PMID: 1899539. PMCID: PMC1886181.
  • Elami A, Laks H, Milgalter E, Sassoon AF. Use of Dacron mesh coated pericardium for aortic augmentation. J Card Surg. 1993 Jul;8(4):488-91. PMID: 8353337.
  • Ward WG, Mikaelian K, Dorey F, Mirra JM, Sassoon A, Holmes EC, Eilber FR, Eckardt JJ. Pulmonary metastases of stage IIB extremity osteosarcoma and subsequent pulmonary metastases. J Clin Oncol. 1994 Sep;12(9):1849-58. PMID: 8083708.
  • Yao K, Singer FR, Roth SI, Sassoon A, Ye C, Giuliano AE. Weight of normal parathyroid glands in patients with parathyroid adenomas. J Clin Endocrinol Metab. 2004 Jul;89(4):3208-13. PMID: 15240594.
  • Buchbinder D, Younes B, Sassoon A, Soni A, Hsieh L, Puthenveetil G, Stites J, Ness- Jorden T, Neudorf S, Nugent D. Inflammatory polyps following successful HLA- matched cord blood transplantation in a patient with X-linked lymphoproliferative syndrome. Pediatr Transplant. 2012 Aug;16(5):E188-91. PMID: 21736679.
  • Micha JP, Sassoon AF, Wong H, Goldstein BH. Prolonged remission of recurrent cervical carcinoma following paclitaxel and carboplatin chemotherapy with paclitaxel maintenance chemotherapy. Anticancer Drugs. 2015 Aug;26(7)793-6. PMID: 25933247.
  • McEachron TA, Kirov I, Wungwattana M, Cortes D, Zabokrtsky KB, Sassoon A, Craig D, Carpten JD, Sender LS. Successful treatment of genetically profiled pediatric extranodal NK/T-cell lymphoma targeting oncogenic STAT3 mutation. Pediatr Blood Cancer. 2016 Apr;63(4):727-30. PMID: 26727971.
  • Buchbinder D, Sassoon A. You GATA look at the marrow! Blood. 2016 Jul 28;128(4):603. PMID: 28092903.
  • Buchbinder D, Sassoon A. A case of bad Carma! Blood. 17 Mar 23;129(12):1737. PMID: 28336733.
  • Bhangoo A, Wang P, Young I, Sassoon A, Taguibao R, Khoury A. A severe case of testotoxicosis in an infant due to a c.1732G>C (p.ASP578His) LHCGR gene mutation associated with nodular Leydig cell hyperplasia. International Journal of Medical
  • Reviews and Case Reports. 2018. DOI: 10.5455/IJMRCR.Leydig-cell-hyperplasia-mutation.
  • Buchbinder DK, Sassoon A, Sy A. Neonatal hyperbilirubinemia: Diagnostic clues from the peripheral blood smear. J Pediatr Hematol Oncol. 2020 Oct;42(7):448. PMID: 32590416.
  • Buchbinder DK, Singh J, Dao T, Sassoon A, Arrieta A. Case report: Pseudomonas can take a toll on a patient. F1000Res. 2021 Jul 1;10:526. PMID: 34381593.
  • Lee W, HaDuong J, Sassoon A, Dao T, Nael A. A liver transplant for local control in a pediatric patient with metastatic TFE3-associated perivascular epithelioid cell tumor (PEComa) to the liver. Case Rep Pathol. 2021 Oct 5;2021:3924565. PMID: 34650822. PMCID: PMC8510831.
  • Yu J, Sassoon AF, Gholizadeh M, Guner YS, Awan S. Rhabdomyosarcoma of the gallbladder. J Pediatr Surg Case Rep. Available online 26 April 2022.